Prednisone Steroids and Alcohol: Is it Safe to Mix?

Medically Reviewed By Kayla Loibl | Last Edited : JUNE  05, 
| 3 Sources

Is It Safe to Mix Prednisone Steroids and Alcohol. It is not advised to mix alcohol with Prednisone (steroids), and it can be dangerous. Alcohol may increase the side effects of prednisone, such as confusion, depression and insomnia. It also increases the risk for stomach problems like ulcers or bleeding in your stomach lining.

If you use prednisone steroids and alcohol , make sure to do so only in moderation--no more than one drink per day for women and two drinks per day for men.

Prednisone Steroids and Alcohol
What is Prednisone (Steroids)?

Prednisone is a steroid that is typically used to treat various conditions, such as asthma, skin allergies and allergic reactions. Prednisone can be taken by mouth or injected into the body. For people who are taking prednisone for an extended period of time, it may become difficult to stop using it once they're ready to do so.

Prednisone is not known as an addictive substance like other steroids. However, Prednisone can cause physical withdrawal symptoms if taken long term. Due to this, stopping “cold turkey” is not advised. Rather, its recommended to work with your doctor about tapering your dose.

- What do some people experience when they stop taking prednisone? Many people find that their symptoms briefly worsen before improving. This is referred to as a rebound effect and it can be very unpleasant for the person who has been on prednisone for an extended period of time. In any event, this will prevent these individuals from immediately stopping use.

- How long does prednisone stay in your system after you have stopped using it? The amount of time depends upon how much someone was initially taking per day but typically between two weeks and three months (or more).

Prednisone usually leaves the body within one week once usage has ceased which means that those with severe asthma or other conditions may need to take another treatment during this period.

Why People Use Prednisone or Steroids

Prednisone, also known as prednisolone, is a medication that has been used to treat various diseases since 1953. Prednisone works by reducing the inflammation in your body and suppressing the immune system.

It can be prescribed for many different conditions including asthma, arthritis, and ulcerative colitis. However, this drug is not without side effects.

Some people use prednisone or steroids without a prescription. They may be able to purchase it online through an unlicensed pharmacy that does not ask for any personal information, making the process anonymous and accessible for everyone!

The popularity of using these drugs is due in part because many chronic illnesses such as asthma, arthritis, and ulcerative colitis can cause long-term pain in those who have them. With this drug they don't need to worry about taking daily medications with unpleasant side effects like weight gain, hair loss, high cholesterol levels and more.

Photo by Kate Kalvach

How Does Alcohol Affect the Body When Mixed with Prednisone (Steroids)?

The most common side effects of prednisone can include nausea and headaches. Prednisone steroids and alcohol  consumption when taken together has been shown to increase the risk for developing an ulcer in the stomach or intestines because it increases acid production in those organs. Prednisone is also known to increase the risk of osteoporosis.

Prednisone steroids and alcohol can lead to mineral imbalances and an increased heart rate, which can be dangerous for those with a history of cardiac conditions or other cardiovascular problems.

Prednisone Steroids and Alcohol may cause withdrawal symptoms, such as depression and insomnia that mimics the effects from alcohol itself.

Prednisone use also increases risks for both ulcers in your stomach or intestines due to its effect on acid production in these organs.

Are There Any Other Side Effects to Worry About When Taking Prednisone Steroids and Alcohol Together?

Mixing prednisone steroids and alcohol can be dangerous because it increases your risk for liver damage and stomach upset problems like ulcers or intestinal bleeding.

In addition, the combination of prednisone steroids and alcohol can lead to overdose. The high doses increase your risk for life-threatening withdrawal symptoms that could result in seizures or loss of consciousness if taken over long periods time.

Alcohol consumption also increases stomach acid production that interacts with Prednisone resulting in an increased risk for ulcers or bleeding from the gastrointestinal tract, another good reason prednisone steroids and alcohol are not a good mix.

The side effects associated with prednisone steroids and alcohol are mixed but combining them together still may not be a good idea because it will make you more at risk for problems like liver damage, stomach upset, and liver disease.

It's important to discuss any questions about what medications you should take before mixing prednisone steroids and alcohol with your doctor so they can help decide whether it is safe or not.

How much is too much when taking Prednisone Steroids and Alcohol?

Can you drink alcohol when taking prednisone, or is it dangerous? This question may seem easy to answer, but the reality of the situation is that there are many factors which need to be considered.

For example, if you are on a low dose of prednisone and only drink occasionally then you should not have any problem with prednisone steroids and alcohol.

However, if you are on a high dose or take it every day for an extended period of time then mixing alcohol with your medication could put you at risk for liver damage and other serious side effects.

This is why it’s important to consult with your doctor before deciding whether or not you should drink alcohol when taking prednisone. A physician will be able to take into consideration the many factors which are associated with this type of medication, and determine if prednisone steroids and alcohol in moderation is safe for you.

What are Some Alternatives for People Who Want to take prednisone steroids and alcohol at the same time?

It is a common question for people who want to drink alcohol but also take steroids at the same time without worrying about what might happen in their bodies when they do both of them together.

Some of the alternatives are:

  • Drinking alcohol with a straw to avoid in-mouth contact.
  • Using an electrolyte drink that will help balance out your fluids and replenish lost nutrients. This is important because drinking alcohol on top of steroids can cause you to lose water weight quickly, which may lead to dehydration. You should also make sure not to mix any other substances like caffeine or energy drinks into your alcoholic beverage while taking steroids since they dehydrate people as well!
  • Staying away from sugary beverages when you're consuming both alcohol and high doses of corticosteroids because it increases the risk for tooth decay due to bacteria growth if consumed too often. The most favorable option would be something carbonated and slightly flavored drinks.


If you are taking prednisone (steroids) and want to drink alcohol, the safest bet is not to mix them together. There are some side effects that can happen if they are mixed with each other such as mood swings or depression.

The best advice would be for those who don't want these possible side effects of mixing prednisone steroids and alcohol at the same time, is just stop taking your medication entirely because it's making me feel depressed and I don't want to be on it anymore?

It may lead to a relapse in addiction. You should consult with your doctor about how this might affect you before doing anything drastic like stopping treatment all together.

Alcoholism Has To Stop!

Alcoholism has adverse effects on its own; more so if it’s mixed with other substances. Nonetheless, you don’t have to live with alcoholism. There are treatment options and programs available to help you. Contact a dedicated treatment provider today.

Lead Writer/Reviewer : Kayla Loibl

Licensed Medical Health Professional 


I am a Mental Health Counselor who is licensed in both New York (LMHC) and North Carolina (LCMHC). I have been working in the Mental Health field since 2015. I have worked in a residential setting, an outpatient program and an inpatient addictions program. I began working in Long Island, NY and then in Guelph, Ontario after moving to Canada. Read More

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