Mixing Mushrooms Alcohol-What are the Dangers?

Medically Reviewed By Kayla Loibl | Last Edited : JULY 12, 
| 4 Sources

Why shouldn’t you mix mushrooms with alcohol?

Mixing mushrooms alcohol can result in a dangerous combination. Though there are no known cases of death, it is not advised to mix the two substances because it could lead to an overdose. People who take this drug may experience some side effects, including nausea, vomiting, headache, sweating or shivering, and seizures.

There are many reasons why you should avoid mixing these two substances together. You want to be safe so that your night doesn't turn out any worse than you expected it would have!

At this time, there are currently clinical trials testing the effectiveness of using mushrooms, also known as Psilocybin, for individuals struggling with an alcohol addiction. It is important to note that this study is in its second phase of trials, and is quite different than using alcohol and mushrooms together.

What are Mushrooms and How Do They Work in Alcohol?

Mushrooms are a type of fungus. They can be either psychedelic mushrooms or they can be mushrooms that do not cause hallucinations. Mushrooms contain psilocybin, a psychoactive compound; taking mushrooms causes the brain to release DMT and serotonin into the bloodstream.

The effect mushrooms have on your body depends on the amount you take, how you take them, whether you are alone or with friends, and other external factors such as your surroundings and where you are taking them.

Taking mushrooms alcohol will magnify the effects of both substances, so it is important to understand and prepare properly for this combination.

Effects of Mixing Mushrooms Alcohol

When you mix mushrooms with alcohol, it can be bad for your health. You risk becoming nauseous and vomiting continuously. Drinking alcohol while under the influence of mushrooms is also a bad idea because both substances will affect every part of your body. There are effects of mixing these two, which could result in death as well if they are not taken seriously.

For example, when you take high doses of mushrooms and alcohol at the same time, it is possible that your central nervous system will shut down, and you won't be able to respond even after consuming too much of either one or both.

Mixing mushrooms with alcohol can also lead to a lot of issues that will cause you to regret the decisions you have made. Depending on how much people drink, some may become violent, while others may suffer from severe memory loss.

You should not overestimate your capabilities when mixing these two substances in order for them not to affect your life adversely. When used in a high dosage, the side effects could include seizures or loss of control over one's actions, resulting in accidents and injuries that could see you permanently disabled.

Risks, Side Effects, and Other Things to Know About Mixing Mushrooms with Alcohol

Mixing mushrooms alcohol can lead to a variety of different negative effects that could be the result of taking too much or mixing the two substances. The negative effects are not always going to happen, but they do need to be discussed in order to safely take both substances together.

These effects include vomiting, nausea, seizures, headaches, shivering, and sweating when taken in combination.

Effects from mixing depressants such as alcohol with hallucinogens like mushrooms include: impairment, dizziness, anxiety, or severe confusion may also occur. Mixing any other drugs with these types of mushrooms should always be avoided because there is a possibility that you will experience an overdose.

You could potentially become extremely ill if too many of these mushrooms are taken with other drugs or if they are taken without food.

Side effects associated with the use of alcohol and hallucinogens include fatigue, loss of appetite, nausea, and vomiting. If you feel sick to your stomach after taking a psychedelic mushroom, then keep in mind that this is completely normal.

However, if you want to prevent sickness from occurring when having a trip on these mushrooms, it is recommended to eat a small amount of food before consuming the drug. Do not mix it with alcohol as this can cause more severe side effects or even lead to alcohol poisoning.

How Long Does the Effect of Mixing Mushrooms and Alcohol Last?

The effects of mixing mushrooms with alcohol can last for up to 6 hours. The person may feel some of its effects for up to 8 hours after taking it. Taking the drug during the day is not recommended because you could have a difficult time functioning at work or school.

If people take this drug at night, they will probably not get much sleep, if any at all. Some people that use this drug will also experience flashbacks once they stop feeling the active effects.

Mixing mushrooms with alcohol can result in dangerous side effects throughout the body, including temporary numbness or loss of muscle control, weak breathing, problems with eye movement, or blurred vision.

Numbness or weakness in your arms and legs are common symptoms that almost everyone experiences when taking these drugs together. It is possible to have a minor allergic reaction, but this usually won't cause any major health problems as long as the person gets medical attention immediately.

What Should I Do If I Mix Mushrooms and Alcohol Together? 

If you experience any problems as a result of mixing mushrooms with alcohol, then you should get medical help right away. In order to treat the negative effects that occur, doctors will have to manage the symptoms based on what the person is experiencing. They may recommend medicine, or they could tell you to drink lots of water until your body can naturally heal itself.

 A trip to the emergency room is typically necessary if someone experiences an overdose associated with this drug combination. If fluids are replaced into the body too quickly, it could lead to serious heart and brain problems as well as death if not given enough time for recovery. Additional treatment will likely be necessary in order to make you feel better!

mushrooms alcoholPhoto by Ash Edmonds

When Should You Seek Medical Attention for Mushroom and Alcohol Intoxication?

There are several different times that you will want to seek medical attention for mushrooms and alcohol poisoning. You need to be sure that if you experience any of these symptoms, you should visit an emergency room before it is too late. Some of these signs include convulsions, coma, or total body paralysis.

If the mushrooms were taken in a high dosage, there could be more severe side effects that could cause permanent damage, such as stroke or heart attack. It is important not to wait until the mushrooms have worn off because you may not survive at all if this occurs!

Mixing Mushrooms Alcohol - Conclusion

Mixing mushrooms with alcohol is risky. It can lead to severe side effects and hallucinations that are hard to control, not to mention the risk of mixing substances in general. For this reason, it's important to know what you're getting into before you decide on taking these two together.

If you have questions about whether or not mushrooms with alcohol will react well together, please consult your doctor beforehand so he or she can discuss any risks and come up with an appropriate treatment plan should something go wrong.

"If you're unsure whether alcohol may be a problem, speak with one of our supportive counselors. With many having first-hand experience they understand the struggle. The free chat is confidential & they are available 24/7."

Lead Writer/Reviewer : Kayla Loibl

Licensed Medical Health Professional 


I am a Mental Health Counselor who is licensed in both New York (LMHC) and North Carolina (LCMHC). I have been working in the Mental Health field since 2015. I have worked in a residential setting, an outpatient program and an inpatient addictions program. I began working in Long Island, NY and then in Guelph, Ontario after moving to Canada. Read More

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